A new ring transformation of 3,4-dihydro-1-methyl-6-phenyl-1,4,5-benzotriazocin-2(1H)-ones into 1-(methylcarbamoyl)methyl-3-phenyl-1H-indazoles.

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6-Chloro-2-methyl-4-phenyl-3-[1-phenyl-5-(2-thien­yl)-4,5-dihydro-1H-pyrazol-3-yl]quinoline

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3-Methyl-1-(3-nitro­phen­yl)-5-phenyl-4,5-dihydro-1H-pyrazole

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TRANSFORMATION OF 2-BENZOYLAMINO-1-(?-NAPHTHYL)PROPAN-1-OL INTO 4-METHYL-1-PHENYL BENZO[f] ISOQUINOLINE RATHER THAN ITS 3-SUBSTITUTED ISOMER

The necessary conditions to transform hydroxyamide (1) and 2-oxazolines (2, 3) into 3- or 4-methyl benzo[f] isoquinolines (4, 5) has been established. The mechanism of these reactions has been proposed claiming the existence of the protonated 2-oxazoline (6) and the styrylamides (7) as intermediates.

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ژورنال

عنوان ژورنال: Chemical and Pharmaceutical Bulletin

سال: 1984

ISSN: 0009-2363,1347-5223

DOI: 10.1248/cpb.32.3252